general news

Demand for prebiotics continues even as FDA wrestles with fibre definition

06 Oct 2017 – By Hank Shultz

Despite uncertainty surrounding the precise definition of fiber, demand for prebiotic ingredients is booming, according to one ingredient supplier.

Nutritional Outlook, AIDP Expands Digestive-Health Portfolio with Anagenix’s Kiwifruit Ingredients

17 April 2017 – By Jennifer Grebow

Ingredients distributor AIDP Inc. (City of Industry, CA) is expanding its digestive-health portfolio thanks to a distribution deal with New Zealand ingredients company Anagenix (Wellington, New Zealand). Anagenix specializes in New Zealand-grown kiwifruit-based ingredients that support digestive health.

One of those ingredients is Actazin, a cold-pressed powdered kiwifruit concentrate that “is a natural source of prebiotics, fiber, enzymes, and polyphenols to support bowel function in a gentler way than harsh laxatives,” AIDP says. “The kiwi-unique enzyme actinadin found in Actazin assists protein digesting, helping people avoid the ‘overfull’ feeling after a protein-rich meal.”

Nutrition Insight, AIDP Expands Digestive Health and “Healthy Aging” Ingredients Portfolio

03 April 2017

Functional ingredients manufacturer AIDP has signed an exclusive license and distribution agreement with agrotechnology company Anagenix to market its kiwifruit-based ingredients, Actazin and Livaux. Anagenix is a New Zealand-based company specializing in the discovery of natural bioactives. Actazin is a cold-pressed powdered kiwi fruit concentrate that is a natural source of prebiotics, fiber, enzymes and polyphenols and may support bowel function.

According to the company, the kiwi-unique enzyme actinadin found in Actazin assists the protein digestion and helps avoid the “overfull” feeling after a protein-rich meal. It is made from Non-GMO Project verified green kiwifruit, sourced in New Zealand. The locally sourced kiwifruit are processed using proprietary technology to ensure retention of the key nutrients and bioactives. Actazin is gluten-free, free of preservatives and added sugar, and is ideal for green food blends and digestive health formulas.

Nutraceuticals World, AIDP Expands Digestive Health Portfolio

29 March 2017

AIDP, City of Industry, CA, has signed an exclusive license and distribution agreement with Anagenix to market its kiwifruit-based ingredients, Actazin and Livaux. Anagenix is a New Zealand-based company specializing in the scientific discovery of natural bioactives which satisfy consumers health and wellness needs.

Actazin is a cold-pressed powdered kiwi fruit concentrate that is a natural source of prebiotics, fiber, enzymes and polyphenols to support bowl function in a gentler way than harsh laxatives. The kiwi-unique enzyme actinadin found in Actazin assists protein digesting, helping people avoid the “overfull” feeling after a protein-rich meal. It is made from Non-GMO Project Verified green kiwifruit, sourced in New Zealand. The locally sourced kiwifruit are gently processed using proprietary technology to ensure retention of the key nutrients and bioactives. Actazin is gluten-free, free of preservatives and added sugar. It is ideal for green food blends, digestive health formulas and more.

Cambridge Commodities launches ACTAZIN and Livaux to the European digestive health and wellness market

16 May 2016 – Nutraceutical Business Review

Anagenix utilise the bioactives found in fruit and plants to make natural and effective products for health and wellness

Nutritional ingredient supplier Cambridge Commodities has announced it is the exclusive European distributor of Anagenix’s ACTAZIN and Livaux.

Anagenix utilises the bioactives found in fruit and plants to make natural and effective products for health and wellness, with an initial focus on digestive health.

Cambridge Commodities Launch New Digestive Health Products

12 May 2016 – Food Ingredients First, by Liesbeth Thijssen

Cambridge Commodities have announced that it is the exclusive European distributor of Anagenix’s Actazin and Livaux, aimed at improving gut health. Anagenix create products based on bioactives contained in fruit and plants for the purpose of promoting health and wellness. Elouan Morel, European sales manager at Cambridge Commodities said: “We are thrilled to be able to bring a product to Europe that is clinically proven and backed up by research.”

Livaux, a non GMO, New Zealand SunGold kiwifruit powder, is described as restoring F. prau for microbiome balance. The company states that the product: “is proven to increase levels of Faecalibacterium prausnitzii (F. prau) in the gut of functionally constipated individuals and improve healthy bowel frequency. Reduced levels of F.prau have been associated with gastrointestinal disorders such as IBS and IBD.” The freeze dried powder is suitable for use in tablet or capsule form.

Actazin Verified by Non-GMO Project

18 August 2015 – Nutraceuticals World

ACTAZIN, a digestive health ingredient from Anagenix (Wellington, New Zealand) and Stratum Nutrition (Saint Charles, MO), has received certification from the Non-GMO Project as being Non-GMO Project Verified.

The Non-GMO Project, an independent, non-profit organization is the world’s foremost organization committed to preserving and building sources of non-GMO products, educating consumers, and providing independent, 3rd party verification that an ingredient is non-GMO. The non-GMO status of ACTAZIN, an ingredient derived from green kiwifruit, increases its opportunities to be included in non-GMO supplements and functional foods, according to the companies.

actazin™ green kiwifruit extract verified by non-gmo project

17 August 2015 – by nutraingredients-usa.com

Actazin™, a digestive health ingredient derived from green kiwifruit, has received certification from the Non-GMO Project as being Non-GMO Project Verified.

science news

Actazin™ Promotes Regularity, Relief of Mild Constipation

Nutraingredients – USA White Paper

Actazin™ is a wholefood-based nutritional ingredient crafted from the nutrient-dense New Zealand green kiwifruit. Actazin™ was recently introduced to the marketplace to address the limitations of the existing digestive health ingredient options. Actazin™ consists of a variety of bioactive components including fiber and polyphenolics, contributing to its prebiotic activity, along with the kiwifruit-unique protein-digesting enzyme, actinidin. Actazin™ use is supported, in part, by the traditional use of whole kiwifruit for routine maintenance of digestive health and for the symptomatic relief of mild constipation.

Food as Medicine: Kiwifruit (Actinidia deliciosa, Actinidiaceae)

July 2017 – American Botanical Council Volume 14, Issue 7, July 2017

Kiwifruit (Actinidia deliciosa, Actinidiaceae), also known by the less common name “Chinese gooseberry,” is one of 50 known species within the genus Actinidia. These species are climbing, woody vines with large, heart-shaped leaves and cream-colored flowers that bloom in the spring. The flowers are dioecious, with male and female blossoms found in separate individuals. The kiwifruit matures in early winter and typically has brown fuzzy skin. Depending on the species, the flesh is either green or yellow, but all species are filled with small black, edible seeds. While A. deliciosa accounts for about 90% of kiwifruit in international trade, two other species are cultivated and sold commercially: A. chinensis and A. arguta. Actinidia deliciosa is the common green kiwifruit. The most common cultivar of A. chinensis is “Hort16A,” known by the brand name ZESPRI, or “gold kiwifruit.” Actinidia arguta is referred to as “baby kiwi” or “grape kiwi” due to the small size of its fruits. Actinidia species are native to southwestern China, but they are now cultivated in New Zealand, the United States, Italy, France, Chile, and Japan.

Actinidin and bloating

22 June 2017 – Wallace et al (2017) A Pilot Randomized Cross-Over Trial to Examine the Effect of Kiwifruit on Satiety and Measures of Gastric Comfort in Healthy Adult Males. Nutrients, 9(7), 639.

Gastrointestinal discomfort is a common condition throughout the world, which often leads to a reduction in quality of life. Gastrointestinal discomfort is a target for potential health claims for foods identified by the European Food Safety Authority (EFSA). Actinidia chinensis var. deliciosa ‘Hayward’ (marketed as Zespri® Green Kiwifruit) is recognised as a fruit that assists with the potential relief of gastrointestinal symptoms [1]. Gastrointestinal discomfort is generally defined as being associated with episodes of abdominal pain or discomfort (such as bloating, abdominal pain/cramp, and borborygmi (rumbling)) in the absence of organic diseases or biochemical abnormalities [2,3]. It is commonly associated with food or drug intake or with alterations of bowel habit and varies among individuals in both frequency and severity. Kiwifruit contains a natural protease (actinidin) which is active in ‘Hayward’ but either inactive or not present in A. chinensis var. chinensis ‘Hort16A’ (marketed as Zespri® Gold Kiwifruit). Actinidin has been shown in in vitro and animal studies to remain active under gastric and ileal conditions [4] and to influence gastric emptying rates [5].

Potential mechanism of action of kiwifruit

30 May 2017 – By Simone Birgit Bayer , Richard Blair Gearry & Lynley Ngaio Drummond

Kiwifruits are recognized as providing relief from constipation and symptoms of constipation-predominant irritable bowel syndrome (IBS-C). However, the underlying mechanisms, specifically in regards to gastrointestinal transit time and motility, are still not completely understood. This review provides an overview on the physiological and pathophysiological processes underlying constipation and IBS-C, the composition of kiwifruit, and recent advances in the research of kiwifruit and abdominal comfort. In addition, gaps in the research are highlighted and scientific studies of other foods with known effects on the gastrointestinal tract are consulted to find likely mechanisms of action. While the effects of kiwifruit fiber are well documented, observed increases in gastrointestinal motility caused by kiwifruit are not fully characterized.

There are a number of identified mechanisms that may be activated by kiwifruit compounds, such as the induction of motility via protease-activated signaling, modulation of microflora, changes in colonic methane status, bile flux, or mediation of inflammatory processes.

Kiwifruit vs psyllium for constipation

April 2017 – Gearry et al (2017). The Effect of Zespritm Green Kiwifruit on Constipation and Abdominal Discomfort: A Controlled Randomized Cross-Over Intervention Study. Gastroenterology, 152(5), S917.

The Effect of Zespri® Green Kiwifruit on Constipation and Abdominal Discomfort: A Controlled Randomized Cross-Over Intervention Study

kiwi for irritable bowel syndrome (ibs) - source: mintel

October 2015 – by Food Science

IBS affects many people and the causes may be quite different for each person. Researchers recently identified Kiwifruit extract, Actazin™ which uses four-way action to support digestive health and well-being.

kiwifruit to rival prunes & probiotics in digestive health?

1 July 2015 – by Ewa Hudson, Head of Health and Wellness Research, Euromonitor International

With the high-protein trend gaining, digestive products containing proteolytic enzymes could gain importance.
Fiber and probiotics have long been dominant as natural digestive aids, but now there is a newcomer popping its head above the parapet: kiwifruit, inherently rich in an enzyme that helps the body to digest proteins and an aid in alleviating constipation. The high protein trend may finally give the kiwifruit the push it needs to enter the realm of mainstream digestive health products.

keep it moving: a digestive system breakthrough

9 June 2015 – by Fred Pescatore, M.D., Logical Health Alternatives

I know this isn’t exactly the sexiest topic to discuss, but it’s one of the most common problems among my patients, especially women. And it shouldn’t be ignored … I’m talking about constipation.
Not only is it simply annoying and uncomfortable when it happens from time to time … when it’s left unchecked, chronic constipation can lead to more serious problems.Let’s face it … people always feel better when they have moved their bowels daily. And, from a medical perspective, daily bowel movements are a necessity. It’s critical for removing toxins from the body and to help expel metabolic waste. Including excess estrogen.I firmly believe that one of the reasons so many women suffer from breast cancer is because many are chronically constipated. And this is just one of MANY potential benefits to regular bowel movements.

actazin™ kiwifruit extract for inner health

1 May 2015 – by Giellepi, Nutrafoods, Volume 14 No.1

The composition of the gut microflora has been found to play important roles in human health and disease. Some polysaccharides, which are slow or non-digestible by humans, are considered as prebiotics because they are selectively fermented by gut bacteria resulting in specific changes in the composition and/or activity of the gastrointestinal microbiota, thus conferring benefit(s) upon the host’s health.

Kiwifruit (Actinidia deliciosa) have been found to enhance gut health by easing constipation, promoting laxation and modulating colonic microbiota. They represent an important source of dietary fibre promoting the adhesion of microorganisms as probiotics to intestinal epithelial cells and subsequent colonization. Some dietary fibre is resistant to digestion in the upper digestive tract and can reach the colon largely intact, where it is broken down by microbial glycosidases to liberate oligo- and mono-saccharides, which are further metabolized by the microbiota ultimately to result in a mixture of organic acids, including short-chain fatty acids (SCFAs) that are a major source of metabolic fuel to the colon.

kiwifruit-derived supplements may boost bowel health for healthy people: rct data

15 April 2015 – by Stephen Daniells, nutraingredients-usa.com

Daily consumption of supplements containing kiwifruit-derived nutritional ingredients may increase bowel movements in healthy individuals, says a new study from New Zealand.

Four weeks of taking supplements containing Actazin or Gold kiwifruit-derived ingredients increased daily bowel movements by more than one bowel movement per week, wrote researchers from The New Zealand Institute for Plant & Food Research Limited and the University of Otago.

growing futures: kiwifruit extract for gut health

by The New Zealand Institute for Plant & Food Research Ltd, 2015

There is increasing demand for products that benefit human health which, combined with consumer preference for products based on natural produce, presents a global opportunity for the functional food market. A key target is digestive health, and products based on fruits and vegetables which are scientifically-proven to support the health of the human gut are highly sought.

Actazin™, developed by Anagenix Ltd and launched in 2011, is a digestive health ingredient derived from kiwifruit. In addition to a number of other bioactive components, Actazin™ contains resistant material that has a prebiotic effect, feeding the ‘good’ bacteria naturally found in the human gut, balancing the digestive system and supporting the body’s immune system. It is sold to natural supplement manufacturers in several countries including the USA, Australia, Canada and Europe.